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Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50043705
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444876(CHEMBL3099608)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50305278(CHEMBL595069 | iodoresiniferatoxin)
Affinity DataKi:  5.90nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196343(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444875(CHEMBL3099609)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50305278(CHEMBL595069 | iodoresiniferatoxin)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444874(CHEMBL3099610)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20287(2-[(4-tert-butylphenyl)methyl]-3-({[(3-fluoro-4-me...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444873(CHEMBL3099611)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444874(CHEMBL3099610)
Affinity DataKi:  94nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20287(2-[(4-tert-butylphenyl)methyl]-3-({[(3-fluoro-4-me...)
Affinity DataKi:  122nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444873(CHEMBL3099611)
Affinity DataKi:  161nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196343(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444876(CHEMBL3099608)
Affinity DataEC50:  0.990nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50444875(CHEMBL3099609)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataEC50:  0.920nMAssay Description:Agonist activity at human TRPV1 expressed in CHO cells assessed as 45Ca2+ uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed