Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50006054
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of thymidylate synthase activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50496578(CHEMBL3134009)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50496577(CHEMBL3134008)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed