Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50005926
TargetCytochrome P450 3A4(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 24nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50: 27nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50: 68nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50: 97nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50495475(CHEMBL3108979)
Affinity DataIC50: 153nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50495474(CHEMBL3108980)
Affinity DataIC50: 172nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50400510(CHEMBL2203399)
Affinity DataIC50: 430nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed