Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50043834
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446952BDBM50446952(CHEMBL3115775)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446953BDBM50446953(CHEMBL3115774)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446954BDBM50446954(CHEMBL3115793)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446953BDBM50446953(CHEMBL3115774)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446961BDBM50446961(CHEMBL3115786)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446952BDBM50446952(CHEMBL3115775)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446955BDBM50446955(CHEMBL3115792)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446965BDBM50446965(CHEMBL3115782)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446964BDBM50446964(CHEMBL3115783)
Affinity DataIC50: 136nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446962BDBM50446962(CHEMBL3115785)
Affinity DataIC50: 141nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446956BDBM50446956(CHEMBL3115791)
Affinity DataIC50: 314nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446960BDBM50446960(CHEMBL3115787)
Affinity DataIC50: 323nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446953BDBM50446953(CHEMBL3115774)
Affinity DataIC50: 402nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446952BDBM50446952(CHEMBL3115775)
Affinity DataIC50: 454nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446976BDBM50446976(CHEMBL3115777 | CHEMBL3115778)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization by spectrofluorometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446969BDBM50446969(CHEMBL3115800)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446957BDBM50446957(CHEMBL3115790)
Affinity DataIC50: 566nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446971BDBM50446971(CHEMBL3115798)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446963BDBM50446963(CHEMBL3115784)
Affinity DataIC50: 638nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446970BDBM50446970(CHEMBL3115799)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446972BDBM50446972(CHEMBL3115797)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431184BDBM50431184(CHEMBL2332567)
Affinity DataIC50: 1.13E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446967BDBM50446967(CHEMBL3115780)
Affinity DataIC50: 1.63E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210259BDBM50210259(all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | Do...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242349BDBM50242349(5,8,11,14,17-EICOSAPENTAENOIC ACID | 5Z,8Z,11Z,14Z...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269534BDBM50269534((Z,Z,Z)-8,11,14-Eicosatrienoic acid | Dihomo-gamma...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269535BDBM50269535(all-cis-icosa-11,14,17-trienoic acid | (11Z,14Z,17...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446974BDBM50446974(CHEMBL3115795)
Affinity DataIC50: 2.15E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446953BDBM50446953(CHEMBL3115774)
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446953BDBM50446953(CHEMBL3115774)
Affinity DataIC50: 2.18E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446976BDBM50446976(CHEMBL3115777 | CHEMBL3115778)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization by spectrofluorometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446952BDBM50446952(CHEMBL3115775)
Affinity DataIC50: 2.73E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446952BDBM50446952(CHEMBL3115775)
Affinity DataIC50: 2.73E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446973BDBM50446973(CHEMBL3115796)
Affinity DataIC50: 4.03E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446958BDBM50446958(CHEMBL3115789)
Affinity DataIC50: 6.06E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446959BDBM50446959(CHEMBL3115788)
Affinity DataIC50: 9.75E+3nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446966BDBM50446966(CHEMBL3115781)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446975BDBM50446975(CHEMBL3115794)
Affinity DataIC50: 1.37E+4nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431185BDBM50431185(CHEMBL2332566)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446968BDBM50446968(CHEMBL3115779)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOxoeicosanoid receptor 1(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446978BDBM50446978(CHEMBL3115773)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed