Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50006057
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496611BDBM50496611(CHEMBL3134416)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496611BDBM50496611(CHEMBL3134416)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496611BDBM50496611(CHEMBL3134416)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496611BDBM50496611(CHEMBL3134416)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496604BDBM50496604(CHEMBL3134406)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496622BDBM50496622(CHEBI:34640 | CHEMBL1739417)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496617BDBM50496617(CHEMBL3134419)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496621BDBM50496621(CHEMBL3134405)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496620BDBM50496620(CHEMBL3134413)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496619BDBM50496619(CHEMBL3134412)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496609BDBM50496609(CHEMBL3134418)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496618BDBM50496618(CHEMBL3134408)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496617BDBM50496617(CHEMBL3134419)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496614BDBM50496614(CHEMBL3134421)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496612BDBM50496612(CHEMBL3134410)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052414BDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061625BDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496605BDBM50496605(CHEMBL3134411)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496607BDBM50496607(CHEMBL3134407)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496606BDBM50496606(CHEMBL3134409)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496614BDBM50496614(CHEMBL3134421)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496613BDBM50496613(CHEMBL3134404)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496609BDBM50496609(CHEMBL3134418)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496608BDBM50496608(CHEBI:66955 | CHEMBL3134414)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496615BDBM50496615(CHEMBL3134417)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496610BDBM50496610(CHEMBL3134420)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496613BDBM50496613(CHEMBL3134404)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496608BDBM50496608(CHEBI:66955 | CHEMBL3134414)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496610BDBM50496610(CHEMBL3134420)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496616BDBM50496616(CHEMBL3134415)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496616BDBM50496616(CHEMBL3134415)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Yersinia pestis)
University of Hawai'I At Hilo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496615BDBM50496615(CHEMBL3134417)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed