Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50005970 Sort by
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495829(CHEMBL3112972)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR by Michaelis-Menten plot analysis in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495829(CHEMBL3112972)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed