Compile Data Set for Download or QSAR
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Found 82 Enz. Inhib. hit(s) with all data for entry = 50043880
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)
Affinity DataIC50:  12nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)
Affinity DataIC50:  29nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)
Affinity DataIC50:  46nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)
Affinity DataIC50:  128nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)
Affinity DataIC50:  135nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447886(CHEMBL3114784)
Affinity DataIC50:  163nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)
Affinity DataIC50:  179nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447885(CHEMBL3114785)
Affinity DataIC50:  200nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447872(CHEMBL3114772)
Affinity DataIC50:  201nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447876(CHEMBL3114768)
Affinity DataIC50:  278nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)
Affinity DataIC50:  300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Affinity DataIC50:  311nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447866(CHEMBL3114778)
Affinity DataIC50:  408nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)
Affinity DataIC50:  423nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)
Affinity DataIC50:  490nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447882(CHEMBL3114762)
Affinity DataIC50:  497nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)
Affinity DataIC50:  564nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447879(CHEMBL3114765)
Affinity DataIC50:  576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447863(CHEMBL3114781)
Affinity DataIC50:  576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)
Affinity DataIC50:  625nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  628nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  770nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447875(CHEMBL3114769)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447865(CHEMBL3114779)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447864(CHEMBL3114780)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447867(CHEMBL3114777)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447877(CHEMBL3114767)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447872(CHEMBL3114772)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447863(CHEMBL3114781)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  3.85E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447885(CHEMBL3114785)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447882(CHEMBL3114762)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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