TargetSphingosine kinase 1(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Competitive inhibition of C-terminal His6-tagged human recombinant SphK1 expressed in baculovirus-infected Sf9 cells using sphingosine as substrateMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Competitive inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of human recombinant SphK1 using sphingosine and ATP as substrate by ADP-Quest kinase assayMore data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 4.20E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 using sphingosine and ATP as substrate by ADP-Quest kinase assayMore data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine and [gamma-32P]ATP as substrateMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 9.80E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 assessed as NBD-S1P formation using NBD-Sph as substrate by HPLC analysisMore data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Penn State Hershey Cancer Institute
Curated by ChEMBL
Penn State Hershey Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of V5-His-tagged human SphK2 expressed in HEK293 cells assessed as S1P production using sphingosine and [gamma-32P]ATP as subs...More data for this Ligand-Target Pair