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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50044159
TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006930(CHEMBL3237244)
Affinity DataKd:  16nMAssay Description:Binding affinity to biotinylated Keap1 DC domain (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006931(CHEMBL2402207)
Affinity DataKd:  1.69E+3nMAssay Description:Binding affinity to biotinylated Keap1 DC domain (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to biotinylated Keap1 DC domain (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006933(CHEMBL3134422)
Affinity DataEC50:  395nMAssay Description:Displacement of FITC-LDEETGEFL-NH2 from Keap1 Kelch domain (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006931(CHEMBL2402207)
Affinity DataEC50:  1.46E+3nMAssay Description:Displacement of FITC-LDEETGEFL-NH2 from Keap1 Kelch domain (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataEC50:  29nMAssay Description:Displacement of FITC-LDEETGEFL-NH2 from Keap1 Kelch domain (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKelch-like ECH-associated protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50006930(CHEMBL3237244)
Affinity DataKd:  26nMAssay Description:Binding affinity to recombinant human Keap1 Kelch domain (321 to 609) expressed in Escherichia coli BL21(DE3)pLysS cells after 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed