Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50044164 Sort by
TargetPoly [ADP-ribose] polymerase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM27543(4-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM27542(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50007192(CHEMBL3237591)
Affinity DataIC50: 58nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins measured without activation by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50007191(CHEMBL3237590)
Affinity DataIC50: 123nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins measured without activation by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed