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Found 30 Enz. Inhib. hit(s) with all data for entry = 50043969
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  83nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  520nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50290835((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50340921(CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50291090((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449207(CHEMBL3127768)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM3534(6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449204(CHEMBL1719330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449205(CHEMBL1277433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50340921(CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50291090((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449208(CHEMBL3127769)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449207(CHEMBL3127768)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM3534(6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM3530(6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449204(CHEMBL1719330)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449205(CHEMBL1277433)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50340921(CHEMBL1761927 | N-(4-(6,7-dimethoxyquinazolin-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50291090((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50290835((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449205(CHEMBL1277433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449204(CHEMBL1719330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM3530(6,7-dimethoxy-N-phenylquinazolin-4-amine | CHEMBL5...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449208(CHEMBL3127769)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50449207(CHEMBL3127768)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Rajiv Gandhi Proudyogiki Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM3534(6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed