Compile Data Set for Download or QSAR
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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50045071
TargetProstaglandin G/H synthase 2(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  280nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProstaglandin G/H synthase 2(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044258(CHEMBL3337489)
Affinity DataIC50:  360nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044256(CHEMBL3337482)
Affinity DataIC50:  400nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044257(CHEMBL3337483)
Affinity DataIC50:  470nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProstaglandin G/H synthase 1(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044258(CHEMBL3337489)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044257(CHEMBL3337483)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
National Research Centre, Dokki

Curated by ChEMBL
LigandPNGBDBM50044256(CHEMBL3337482)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed