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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50044182
TargetHeat shock protein HSP 90-alpha(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of human HSP90alpha expressed in yeast assessed as growth inhibition of host after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-beta(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of human HSP90beta expressed in yeast assessed as growth inhibition of host after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-beta(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008055(CHEMBL3234416)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human HSP90beta expressed in yeast assessed as growth inhibition of host after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-alpha(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008055(CHEMBL3234416)
Affinity DataIC50:  3.09E+5nMAssay Description:Inhibition of human HSP90alpha expressed in yeast assessed as growth inhibition of host after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-beta(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataKd:  152nMAssay Description:Binding affinity to N-terminal FLAG-tagged human recombinant HSP90beta expressed in Escherichia coli BL21(DE3) by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHeat shock protein HSP 90-alpha(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataKd:  714nMAssay Description:Binding affinity to N-terminal FLAG-tagged human recombinant HSP90alpha expressed in Escherichia coli BL21(DE3) by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)