Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50044223
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228080(2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009625(CHEMBL3234850)
Affinity DataIC50:  68nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009635(CHEMBL3234861)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009631(CHEMBL3234856)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009587(CHEMBL3234847)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009588(CHEMBL3234848)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50:  244nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009589(CHEMBL3234849)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009633(CHEMBL3234859)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009630(CHEMBL3234855)
Affinity DataIC50:  380nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009636(CHEMBL3234862)
Affinity DataIC50:  470nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009627(CHEMBL3234852)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009629(CHEMBL3234854)
Affinity DataIC50:  670nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009586(CHEMBL3234846)
Affinity DataIC50:  1.11E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009628(CHEMBL3234853)
Affinity DataIC50:  1.32E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009626(CHEMBL3234851)
Affinity DataIC50:  1.44E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009634(CHEMBL3234860)
Affinity DataIC50:  1.53E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009585(CHEMBL3234845)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of estrogen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of estrogen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of progesterone receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human ERG (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437638(CHEMBL2407661)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009632(CHEMBL3234857)
Affinity DataIC50:  6.74E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of human ERG (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009584(CHEMBL3234863)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009583(CHEMBL3234858)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed