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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50044292
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataIC50:  820nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011523(CHEMBL3262555)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50350224(CHEMBL1812011)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011524(CHEMBL2396784)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011528(CHEMBL2396790)
Affinity DataIC50:  2.99E+4nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011530(CHEMBL2396791)
Affinity DataIC50:  2.99E+4nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011526(CHEMBL2396788)
Affinity DataIC50:  4.72E+4nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human factor-11a catalytic domain-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011531(CHEMBL2396792)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011532(CHEMBL3262556)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011533(CHEMBL3262557)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011529(CHEMBL2396789)
Affinity DataIC50:  3.84E+5nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to fluorescein-EGR-labeled human factor-11a by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011523(CHEMBL3262555)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to fluorescein-EGR-labeled human factor-11a by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed