Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50044128
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004424BDBM50004424(CHEMBL3238463)
Affinity DataIC50: 4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004425BDBM50004425(CHEMBL3238207)
Affinity DataIC50: 6nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004426BDBM50004426(CHEMBL3238465)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004427BDBM50004427(CHEMBL3238471)
Affinity DataIC50: 30nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004428BDBM50004428(CHEMBL3238466)
Affinity DataIC50: 33nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004429BDBM50004429(CHEMBL3238468)
Affinity DataIC50: 34nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004425BDBM50004425(CHEMBL3238207)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50394748BDBM50394748(CHEMBL2163347)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004430BDBM50004430(CHEMBL3238469)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004431BDBM50004431(CHEMBL3238208)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004432BDBM50004432(CHEMBL3238464)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004429BDBM50004429(CHEMBL3238468)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004450BDBM50004450(CHEMBL3238209)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004451BDBM50004451(CHEMBL3238213)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004450BDBM50004450(CHEMBL3238209)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50394748BDBM50394748(CHEMBL2163347)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004452BDBM50004452(CHEMBL3238211)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004453BDBM50004453(CHEMBL3238470)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004432BDBM50004432(CHEMBL3238464)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004431BDBM50004431(CHEMBL3238208)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004451BDBM50004451(CHEMBL3238213)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004452BDBM50004452(CHEMBL3238211)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004443BDBM50004443(CHEMBL3238473)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004444BDBM50004444(CHEMBL3238474)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004445BDBM50004445(CHEMBL3238475)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004446BDBM50004446(CHEMBL3238210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004448BDBM50004448(CHEMBL3238467)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004449BDBM50004449(CHEMBL3238472)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004446BDBM50004446(CHEMBL3238210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004447BDBM50004447(CHEMBL3238212)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004443BDBM50004443(CHEMBL3238473)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004444BDBM50004444(CHEMBL3238474)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004445BDBM50004445(CHEMBL3238475)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004448BDBM50004448(CHEMBL3238467)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004430BDBM50004430(CHEMBL3238469)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004427BDBM50004427(CHEMBL3238471)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004449BDBM50004449(CHEMBL3238472)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004447BDBM50004447(CHEMBL3238212)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004424BDBM50004424(CHEMBL3238463)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004426BDBM50004426(CHEMBL3238465)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004428BDBM50004428(CHEMBL3238466)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-LOX in human whole blood assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins followed by A23187 inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004453BDBM50004453(CHEMBL3238470)
Affinity DataIC50: 8.36E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed