Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50044299
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012008BDBM50012008(CHEMBL3263286)
Affinity DataIC50: 0.25nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012003BDBM50012003(CHEMBL3263282)
Affinity DataIC50: 1.5nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011988BDBM50011988(CHEMBL3263270)
Affinity DataIC50: 2nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011821BDBM50011821(CHEMBL3263256)
Affinity DataIC50: 4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011986BDBM50011986(CHEMBL3263268)
Affinity DataIC50: 6.5nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011990BDBM50011990(CHEMBL3263272)
Affinity DataIC50: 6.60nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011987BDBM50011987(CHEMBL3263269)
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at human CCR2 expressed in THP1 cells assessed as inhibition of MCP-1 induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011987BDBM50011987(CHEMBL3263269)
Affinity DataIC50: 11nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011986BDBM50011986(CHEMBL3263268)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human CCR2 expressed in THP1 cells assessed as inhibition of MCP-1 induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011967BDBM50011967(CHEMBL3263259)
Affinity DataIC50: 14nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011820BDBM50011820(CHEMBL3263255)
Affinity DataIC50: 16nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011903BDBM50011903(CHEMBL3263258)
Affinity DataIC50: 16nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011989BDBM50011989(CHEMBL3263271)
Affinity DataIC50: 27nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011969BDBM50011969(CHEMBL3263261)
Affinity DataIC50: 29nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012001BDBM50012001(CHEMBL3263280)
Affinity DataIC50: 30nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012007BDBM50012007(CHEMBL3263285)
Affinity DataIC50: 35nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50424032BDBM50424032(CHEMBL2313765)
Affinity DataIC50: 49nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011822BDBM50011822(CHEMBL3263257)
Affinity DataIC50: 59nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012000BDBM50012000(CHEMBL3263279)
Affinity DataIC50: 62nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011992BDBM50011992(CHEMBL3263274)
Affinity DataIC50: 81nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011969BDBM50011969(CHEMBL3263261)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at human CCR2 expressed in THP1 cells assessed as inhibition of MCP-1 induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011994BDBM50011994(CHEMBL3263276)
Affinity DataIC50: 180nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012002BDBM50012002(CHEMBL3263281)
Affinity DataIC50: 190nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011991BDBM50011991(CHEMBL3263273)
Affinity DataIC50: 330nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011993BDBM50011993(CHEMBL3263275)
Affinity DataIC50: 340nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012005BDBM50012005(CHEMBL3263283)
Affinity DataIC50: 370nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011968BDBM50011968(CHEMBL3263260)
Affinity DataIC50: 1.28E+3nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012006BDBM50012006(CHEMBL3263284)
Affinity DataIC50: 2.13E+3nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011985BDBM50011985(CHEMBL3263267)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012008BDBM50012008(CHEMBL3263286)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011982BDBM50011982(CHEMBL3263264)
Affinity DataIC50: 3.17E+3nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011980BDBM50011980(CHEMBL3263262)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012003BDBM50012003(CHEMBL3263282)
Affinity DataIC50: 5.80E+3nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011984BDBM50011984(CHEMBL3263266)
Affinity DataIC50: 1.61E+4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011983BDBM50011983(CHEMBL3263265)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011997BDBM50011997(CHEMBL3263277)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011999BDBM50011999(CHEMBL3263278)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011981BDBM50011981(CHEMBL3263263)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of labeled MCP-1 from human CCR2 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012007BDBM50012007(CHEMBL3263285)
Affinity DataIC50: 2.90E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012000BDBM50012000(CHEMBL3263279)
Affinity DataIC50: 4.30E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012002BDBM50012002(CHEMBL3263281)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011820BDBM50011820(CHEMBL3263255)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012001BDBM50012001(CHEMBL3263280)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012006BDBM50012006(CHEMBL3263284)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed