Compile Data Set for Download or QSAR
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Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50044374
TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015247(CHEMBL3262766)
Affinity DataIC50:  110nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015246(CHEMBL3262765)
Affinity DataIC50:  170nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015242(CHEMBL3262758)
Affinity DataIC50:  190nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015240(CHEMBL3262756)
Affinity DataIC50:  220nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015239(CHEMBL3262755)
Affinity DataIC50:  340nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015236(CHEMBL3262752)
Affinity DataIC50:  340nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015241(CHEMBL3262757)
Affinity DataIC50:  360nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015238(CHEMBL3262754)
Affinity DataIC50:  380nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015237(CHEMBL3262753)
Affinity DataIC50:  440nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015244(CHEMBL3262762)
Affinity DataIC50:  630nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteasome subunit beta type-7(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50015243(CHEMBL3262761)
Affinity DataIC50:  950nMAssay Description:Inhibition of chymotrypsin-like enzyme activity of purified human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed