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Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50006128 Sort by
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497099(CHEMBL3263459)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497108(CHEMBL3263466)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497092(CHEMBL3263471)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497091(CHEMBL3263464)
Affinity DataIC50: 23nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497091(CHEMBL3263464)
Affinity DataIC50: 23nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497101(CHEMBL3263463)
Affinity DataIC50: 24nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497101(CHEMBL3263463)
Affinity DataIC50: 26nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497096(CHEMBL3263479)
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497101(CHEMBL3263463)
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497108(CHEMBL3263466)
Affinity DataIC50: 34nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497105(CHEMBL3263478)
Affinity DataIC50: 39nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497094(CHEMBL3263462)
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497106(CHEMBL3263465)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497105(CHEMBL3263478)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497096(CHEMBL3263479)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497107(CHEMBL3263458)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497100(CHEMBL3263460)
Affinity DataIC50: 57nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497095(CHEMBL3263472)
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497105(CHEMBL3263478)
Affinity DataIC50: 65nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase V106A mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497094(CHEMBL3263462)
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497093(CHEMBL3263461)
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497096(CHEMBL3263479)
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497092(CHEMBL3263471)
Affinity DataIC50: 83nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497095(CHEMBL3263472)
Affinity DataIC50: 89nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497105(CHEMBL3263478)
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497093(CHEMBL3263461)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497102(CHEMBL3263470)
Affinity DataIC50: 131nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497094(CHEMBL3263462)
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497093(CHEMBL3263461)
Affinity DataIC50: 180nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497104(CHEMBL3263476)
Affinity DataIC50: 190nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497103(CHEMBL3263475)
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497106(CHEMBL3263465)
Affinity DataIC50: 218nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497102(CHEMBL3263470)
Affinity DataIC50: 270nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497103(CHEMBL3263475)
Affinity DataIC50: 288nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50033885(CHEMBL3263468)
Affinity DataIC50: 540nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497095(CHEMBL3263472)
Affinity DataIC50: 960nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497104(CHEMBL3263476)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497098(CHEMBL3263477)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497102(CHEMBL3263470)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497097(CHEMBL3263469)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase L1001 mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50497092(CHEMBL3263471)
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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