Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50044448
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017359(CHEMBL3288265)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017358(CHEMBL3286416)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017364(CHEMBL3288273)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017362(CHEMBL3288268)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017350(CHEMBL3288281)
Affinity DataIC50:  20nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human ERG tail current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017360(CHEMBL3288266)
Affinity DataIC50:  30nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017365(CHEMBL3288274)
Affinity DataIC50:  30nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017357(CHEMBL3288264)
Affinity DataIC50:  60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017356(CHEMBL3288263)
Affinity DataIC50:  60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017349(CHEMBL3288280)
Affinity DataIC50:  60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017361(CHEMBL3288267)
Affinity DataIC50:  60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017351(CHEMBL3288282)
Affinity DataIC50:  70nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017353(CHEMBL3288271)
Affinity DataIC50:  80nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017352(CHEMBL3288270)
Affinity DataIC50:  100nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017366(CHEMBL3288275)
Affinity DataIC50:  110nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017348(CHEMBL3288279)
Affinity DataIC50:  140nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017354(CHEMBL3288261)
Affinity DataIC50:  160nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017355(CHEMBL3288262)
Affinity DataIC50:  230nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017367(CHEMBL3288276)
Affinity DataIC50:  240nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017368(CHEMBL3288277)
Affinity DataIC50:  240nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017363(CHEMBL3288272)
Affinity DataIC50:  260nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50017369(CHEMBL3288278)
Affinity DataIC50:  880nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed