Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50044468
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018286(CHEMBL3290335)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018284(CHEMBL3290333)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018282(CHEMBL3290331 | CHEBI:79045)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSmoothened homolog(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018282(CHEMBL3290331 | CHEBI:79045)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at smoothened (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018273(CHEMBL3290322)
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018285(CHEMBL3290334)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018275(CHEMBL3290324)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018281(CHEMBL3290330)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50268610(6-[(R)-4-(4-Benzylphthalazin-1-yl)-2-methylpiperaz...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018276(CHEMBL3290325)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018271(CHEMBL3290320)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018283(CHEMBL3290332)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50158336(FINGOLIMOD HYDROCHLORIDE | 2-amino-2-(4-octylphene...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018286(CHEMBL3290335)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at smoothened (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018277(CHEMBL3290326)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018278(CHEMBL3290327)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018279(CHEMBL3290328)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018280(CHEMBL3290329)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50268609(6-[(S)-4-(4-Benzylphthalazin-1-yl)-2-methylpiperaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50269082(6-[4-(4-Benzylphthalazin-1-yl)piperazin-1-yl]nicot...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018272(CHEMBL3290321)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018274(CHEMBL3290323)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50158336(FINGOLIMOD HYDROCHLORIDE | 2-amino-2-(4-octylphene...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of S1PL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018270(CHEMBL1852164)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of S1PL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50018269(CHEMBL488336)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of S1PL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed