Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50033458
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345760BDBM50345760(1-(Benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-i...)
Affinity DataKi:  2.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345777BDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataKi:  2.56nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345758BDBM50345758(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(piperazin...)
Affinity DataKi:  2.58nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345754BDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  2.97nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345763BDBM50345763(1-(4-Chloro benzenesulfonyl)-5-(4-methylpiperazin-...)
Affinity DataKi:  3.02nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345762BDBM50345762(1-(3-trifluoromethyl benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  3.15nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345772BDBM50345772(1-(4-Fluoro benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  3.21nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345753BDBM50345753(3-Chloro-1-(2,4-difluorobenzenesulfonyl)-5-(4-meth...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345769BDBM50345769(1-Benzenesulfonyl-5-(4-methylpiperazin-1-yl-methyl...)
Affinity DataKi:  3.83nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345756BDBM50345756(1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-3-c...)
Affinity DataKi:  4.16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345776BDBM50345776(1-(2,3-Dichlorobenzenesulfonyl)-5-(4-ethylpiperazi...)
Affinity DataKi:  5.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345757BDBM50345757(3-Chloro-1-(2,4-difluoro benzenesulfonyl)-5-(piper...)
Affinity DataKi:  5.57nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345775BDBM50345775(1-(3-trifluoromethyl benzenesulfonyl)-5-(4-ethylpi...)
Affinity DataKi:  5.72nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345774BDBM50345774(1-(4-Isopropyl benzenesulfonyl)-5-(4-ethylpiperazi...)
Affinity DataKi:  5.81nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345761BDBM50345761(1-(2-Bromo benzenesulfonyl)-5-(piperazin-1-yl-meth...)
Affinity DataKi:  7.77nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345765BDBM50345765(1-(2-Bromo benzenesulfonyl)-5-(4-methylpiperazin-1...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345755BDBM50345755(1-(4-Chlorobenzenesulfonyl)-3-chloro-5-(4-methyl p...)
Affinity DataKi:  9.33nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345773BDBM50345773(1-(4-Methyl benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345766BDBM50345766(1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-5-(...)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345771BDBM50345771(1-(2,4-Difluoro benzenesulfonyl)-5-(4-ethylpiperaz...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345768BDBM50345768(1-(4-Fluoro benzenesulfonyl)-5-(4-methylpiperazin-...)
Affinity DataKi:  14.6nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345759BDBM50345759(1-(4-Isopropyl benzenesulfonyl)-5-(piperazin-1-yl-...)
Affinity DataKi:  14.9nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345767BDBM50345767(1-[4-(Isopropyl benzenesulfonyl)]-5-(4-methylpiper...)
Affinity DataKi:  17.9nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345764BDBM50345764(1-(2,3-Dichloro benzenesulfonyl)-5-(4-methylpipera...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345770BDBM50345770(1-(4-Chloro benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  28.2nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345751BDBM50345751(1-benzyl-5-(4-ethylpiperazin-1-yl-methyl)-1H-indol...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345752BDBM50345752(1-Benzoyl-5-(4-methylpiperazin-1-yl-methyl)-1H-ind...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345777BDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345754BDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345754BDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345777BDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345754BDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345777BDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed