TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
Affinity DataIC50: 5.69E+3nMAssay Description:Inhibition of ASK1More data for this Ligand-Target Pair
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of INSMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.08E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.08E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.51E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.75E+4nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.26E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.44E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair