Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50032967
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50333628((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337068((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(thiophen-3-yl)...)
Affinity DataIC50: 0.772nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337089(((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((2-(thiophen-3-yl...)
Affinity DataIC50: 1.11nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337067((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(thiophen-2-yl)...)
Affinity DataIC50: 1.14nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337075((2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(4-methyl-3-(...)
Affinity DataIC50: 1.28nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337086((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((2-(furan-2-yl)thi...)
Affinity DataIC50: 1.42nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337074((2S,3R,4R,5S,6R)-2-(3-((5-(Furan-2-yl)thiazol-2-yl...)
Affinity DataIC50: 1.43nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337066((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-3-yl)thi...)
Affinity DataIC50: 1.57nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337076((2S,3R,4R,5S,6R)-2-(4-Bromo-3-((5-(furan-2-yl)thia...)
Affinity DataIC50: 1.89nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337088((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((2-(thiophen-2-yl)...)
Affinity DataIC50: 2.79nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337070((2S,3R,4R,5S,6R)-2-(3-(2,5'-Bithiazol-2'-ylmethyl)...)
Affinity DataIC50: 3.13nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337087((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((2-(furan-3-yl)thi...)
Affinity DataIC50: 4.47nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337051((2S,3R,4R,5S,6R,E)-2-(3-((5-(but-2-en-2-yl)thiazol...)
Affinity DataIC50: 4.69nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337048((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-hexylthiazol-2-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337078((2S,3R,4R,5S,6R)-2-(4-Fluoro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 6.11nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337077((2S,3R,4R,5S,6R)-2-(4-Bromo-3-((5-(thiophen-3-yl)t...)
Affinity DataIC50: 6.36nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337079((2S,3R,4R,5S,6R)-2-(4-Fluoro-3-((5-(thiazol-3-yl)t...)
Affinity DataIC50: 7.36nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337058((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(pentyloxy)thia...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337065((2S,3R,4R,5S,6R)-2-(3-((5-(biphenyl-4-yl)thiazol-2...)
Affinity DataIC50: 9.31nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337053((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-cyclopentylthia...)
Affinity DataIC50: 9.71nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337080((2S,3R,4R,5S,6R)-2-(3-((5-(Furan-2-yl)thiazol-2-yl...)
Affinity DataIC50: 9.73nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337052((2S,3R,4R,5S,6R)-2-(3-((5-Allylthiazol-2-yl)methyl...)
Affinity DataIC50: 11.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337056((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-propoxythiazol-...)
Affinity DataIC50: 12.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337049((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-heptylthiazol-2...)
Affinity DataIC50: 12.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337069((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(5-chlorothioph...)
Affinity DataIC50: 13.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337047((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-pentylthiazol-2...)
Affinity DataIC50: 13.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337063((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-phenylthiazol-2...)
Affinity DataIC50: 13.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337071((2S,3R,4R,5S,6R)-2-(3-((5-(1,3,4-Thiadiazol-2-yl)t...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337081((2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(3-((5-(thiop...)
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337045((2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-ethylthiazol-2-...)
Affinity DataIC50: 16.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337055((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-ethoxythiazol-2...)
Affinity DataIC50: 18.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337062((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(pentylthio)thi...)
Affinity DataIC50: 18.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337057((2S,3R,4R,5S,6R)-2-(3-((5-butoxythiazol-2-yl)methy...)
Affinity DataIC50: 19.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337064((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(4-fluorophenyl...)
Affinity DataIC50: 21.2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337082((2S,3R,4R,5S,6R)-2-(3-((5-(Furan-2-yl)thiazol-2-yl...)
Affinity DataIC50: 22.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337054((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-cyclohexylthiaz...)
Affinity DataIC50: 25.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337059((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(ethylthio)thia...)
Affinity DataIC50: 30.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337083(2-((5-(Furan-2-yl)thiazol-2-yl)methyl)-4-((2S,3R,4...)
Affinity DataIC50: 36.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337072(Ethyl2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydr...)
Affinity DataIC50: 50.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337050((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-isopropylthiazo...)
Affinity DataIC50: 51.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337085((2S,3R,4R,5S,6R)-2-(4-Cyclopropyl-3-((5-(furan-2-y...)
Affinity DataIC50: 54.8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337060((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(propylthio)thi...)
Affinity DataIC50: 56.4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337061((2S,3R,4R,5S,6R)-2-(3-((5-(Butylthio)thiazol-2-yl)...)
Affinity DataIC50: 58.7nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337046((2S,3R,4R,5S,6R)-2-(3-((5-Butylthiazol-2-yl)methyl...)
Affinity DataIC50: 119nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337084(2-((5-(Thiophen-3-yl)thiazol-2-yl)methyl)-4-((2S,3...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337073(2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed