Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50032970
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337121BDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337123BDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337122BDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337118BDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337117BDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337122BDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337120BDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337119BDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337124BDBM50337124(4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-tria...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307884BDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10016BDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337125BDBM50337125(4-(((4',6-dicyanobiphenyl-3-yl)(4H-1,2,4-triazol-4...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10020BDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337121BDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307886BDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50: 2nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337120BDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307884BDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337119BDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 17nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337123BDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)
Affinity DataIC50: 22nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307886BDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50: 35nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10020BDBM10020(YM511-based dual aromatase-sulfatase inhibitor (DA...)
Affinity DataIC50: 39nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337124BDBM50337124(4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-tria...)
Affinity DataIC50: 55nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10017BDBM10017(YM511 Analog 4 | (4-{[(4-cyanophenyl)(4H-1,2,4-tri...)
Affinity DataIC50: 100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337125BDBM50337125(4-(((4',6-dicyanobiphenyl-3-yl)(4H-1,2,4-triazol-4...)
Affinity DataIC50: 240nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10017BDBM10017(YM511 Analog 4 | (4-{[(4-cyanophenyl)(4H-1,2,4-tri...)
Affinity DataIC50: 277nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337117BDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337118BDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed