Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50039489 Sort by
LigandPNGBDBM50125935(CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50125935(CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50378948(CHEMBL2011431 | US9394290, 36)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)
Affinity DataIC50: 17nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378954(CHEMBL2011437 | US9394290, 42)
Affinity DataIC50: 29nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378950(CHEMBL2011433 | US9394290, 38)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50378937(CHEMBL2011253 | US9394290, 23)
Affinity DataIC50: 42nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378960(CHEMBL2011242 | US9394290, 5)
Affinity DataIC50: 61nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378946(CHEMBL2011264 | US9394290, 34)
Affinity DataIC50: 62nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 67nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50378962(CHEMBL2011244 | US9394290, 7)
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378947(CHEMBL2011430)
Affinity DataIC50: 73nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378943(CHEMBL2011261 | US9394290, 31)
Affinity DataIC50: 75nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378952(CHEMBL2011435 | US9394290, 40)
Affinity DataIC50: 76nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378942(CHEMBL2011260 | US9394290, 30)
Affinity DataIC50: 95nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378969(CHEMBL2011247 | US9394290, 15)
Affinity DataIC50: 101nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378971(CHEMBL2011248 | US9394290, 17)
Affinity DataIC50: 106nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378970(CHEMBL273205 | US9394290, 16)
Affinity DataIC50: 110nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378944(CHEMBL2011262 | US9394290, 32)
Affinity DataIC50: 126nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 127nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378941(CHEMBL2011257 | US9394290, 27)
Affinity DataIC50: 139nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335360(5-((1H-imidazol-1-yl)methyl)-2-phenylpyridine | CH...)
Affinity DataIC50: 152nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378951(CHEMBL2011434 | US9394290, 39)
Affinity DataIC50: 167nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378966(CHEMBL402298 | US9394290, 12)
Affinity DataIC50: 167nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 168nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378964(CHEMBL272749 | US9394290, 9)
Affinity DataIC50: 213nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)
Affinity DataIC50: 237nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378974(CHEMBL2011252 | US9394290, 21)
Affinity DataIC50: 246nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378938(CHEMBL2011254 | US9394290, 24)
Affinity DataIC50: 246nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378948(CHEMBL2011431 | US9394290, 36)
Affinity DataIC50: 251nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378949(CHEMBL2011432 | US9394290, 37)
Affinity DataIC50: 269nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378949(CHEMBL2011432 | US9394290, 37)
Affinity DataIC50: 281nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378963(CHEMBL2011245 | US9394290, 8)
Affinity DataIC50: 320nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378965(CHEMBL402522 | US9394290, 10)
Affinity DataIC50: 329nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378939(CHEMBL2011255 | US9394290, 25)
Affinity DataIC50: 362nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378945(CHEMBL2011263 | US9394290, 33)
Affinity DataIC50: 362nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378955(CHEMBL2011250 | US9394290, 19)
Affinity DataIC50: 409nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378947(CHEMBL2011430)
Affinity DataIC50: 416nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378941(CHEMBL2011257 | US9394290, 27)
Affinity DataIC50: 487nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378953(CHEMBL2011436 | US9394290, 41)
Affinity DataIC50: 500nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378959(CHEMBL2011241 | US9394290, 1a)
Affinity DataIC50: 500nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378940(CHEMBL2011256 | US9394290, 26)
Affinity DataIC50: 502nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378971(CHEMBL2011248 | US9394290, 17)
Affinity DataIC50: 528nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378972(CHEMBL2011249 | US9394290, 18)
Affinity DataIC50: 542nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378961(CHEMBL2011243 | US9394290, 6)
Affinity DataIC50: 576nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50378975(CHEMBL2010808 | US9394290, 22)
Affinity DataIC50: 611nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 663nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50378973(CHEMBL2011251 | US9394290, 20)
Affinity DataIC50: 782nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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