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Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50039502
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379157(CHEMBL1234899 | US8703811, 57)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379150(CHEMBL2012961)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379152(CHEMBL2012963)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379153(CHEMBL2012964)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 using S-mephenytoin as substrate after 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 using S-mephenytoin as substrate after 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 using midazolam as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 using midazolam as substrate after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379155(CHEMBL2012966)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379148(CHEMBL2012831 | US8703811, 67)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379154(CHEMBL2012965)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379147(CHEMBL2012830 | US8703811, 49)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379146(CHEMBL2012829 | US8703811, 31 | US8703811, 32)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379145(CHEMBL2012827 | US8703811, 35)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379144(CHEMBL2012826 | US8703811, 29)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379143(CHEMBL2012825 | US8703811, 38)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379142(CHEMBL2012824 | US8703811, 23)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379141(CHEMBL2012823 | US8703811, 36)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379140(CHEMBL2012821 | US8703811, 25)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379139(CHEMBL2012820 | US8703811, 24)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379137(CHEMBL2012822 | US8703811, 11)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379138(CHEMBL2012951)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379151(CHEMBL2012962)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379149(CHEMBL2012941)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50379156(CHEMBL2012958 | Genz-669178)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed