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Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50040363
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393102(CHEMBL2152917 | US10231967, Example 20t | US886591...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393107(CHEMBL2152921)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393107(CHEMBL2152921)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393106(CHEMBL2152920 | US10231967, Example 72 | US9918985...)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393105(CHEMBL2152919)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393103(CHEMBL2151058 | US10231967, Example 20z | US991898...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393105(CHEMBL2152919)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393106(CHEMBL2152920 | US10231967, Example 72 | US9918985...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393101(CHEMBL2152916 | US10231967, Example 20i | US886591...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393101(CHEMBL2152916 | US10231967, Example 20i | US886591...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393103(CHEMBL2151058 | US10231967, Example 20z | US991898...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393102(CHEMBL2152917 | US10231967, Example 20t | US886591...)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed