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Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50042579
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50295926(4'-O-methylhonokiol, MH | 4-methoxyhonokiol | ...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(CHEMBL32362 | tetrahydro-magnolol)
Affinity DataKi:  416nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(CHEMBL32362 | tetrahydro-magnolol)
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataKi:  3.14E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataKi:  3.15E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataKi:  5.61E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataKi:  6.46E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428093(8,9-dihydroxydihydro-magnolol | CHEMBL2331642)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428093(8,9-dihydroxydihydro-magnolol | CHEMBL2331642)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetG-protein coupled receptor 55(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at GPR55 (unknown origin) expressed in CHO cells assessed as inhibition of LPI-induced beta-arrestin translocation after 90 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(CHEMBL32362 | tetrahydro-magnolol)
Affinity DataEC50:  170nMAssay Description:Partial agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataEC50:  1.83E+4nMAssay Description:Partial agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataEC50:  8.73E+3nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataEC50:  3.28E+3nMAssay Description:Partial agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(CHEMBL32362 | tetrahydro-magnolol)
Affinity DataEC50:  9.01E+3nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed