Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50042579 Sort by
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataEC50:  3.28E+3nMAssay Description:Partial agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(tetrahydro-magnolol | CHEMBL32362)
Affinity DataEC50:  170nMAssay Description:Partial agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataEC50:  1.83E+4nMAssay Description:Partial agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 55(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at GPR55 (unknown origin) expressed in CHO cells assessed as inhibition of LPI-induced beta-arrestin translocation after 90 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataEC50:  8.73E+3nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(tetrahydro-magnolol | CHEMBL32362)
Affinity DataEC50:  9.01E+3nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50295926(Magreth-14a | 5,3'-Diallyl-4'-methoxy-biphenyl-2-o...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(tetrahydro-magnolol | CHEMBL32362)
Affinity DataKi:  416nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428092(tetrahydro-magnolol | CHEMBL32362)
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataKi:  3.14E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM78304(2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...)
Affinity DataKi:  3.15E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKi:  5.61E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKi:  6.46E+3nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428093(8,9-dihydroxydihydro-magnolol | CHEMBL2331642)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428091(CHEMBL179840)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50428093(8,9-dihydroxydihydro-magnolol | CHEMBL2331642)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB1 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed