Found 40 Enz. Inhib. hit(s) with all data for entry = 50043610 TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
