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Found 18 Enz. Inhib. hit(s) with all data for entry = 50043676
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444531(CHEMBL3099680)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444531(CHEMBL3099680)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444538(CHEMBL1313977)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444532(CHEMBL3099679)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444534(CHEMBL3099594)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444537(CHEMBL3099590)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444535(CHEMBL3099592)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444539(CHEMBL3099593)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444537(CHEMBL3099590)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444540(CHEMBL1594316)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444533(CHEMBL3099678)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444536(CHEMBL3099591)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50078827(2-(pyridin-3-yl)-1H-benzo[d]imidazole | 2-Pyridin-...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444535(CHEMBL3099592)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444532(CHEMBL3099679)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50180740(2-(furan-2-yl)-1H-benzo[d]imidazole | CHEMBL201094...)
Affinity DataIC50:  2.07E+5nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444536(CHEMBL3099591)
Affinity DataIC50:  2.37E+5nMAssay Description:Inhibition of recombinant 5-lipoxygenase (unknown origin) expressed in Escherichia coli BL21(DE3) using arachidonic acid as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50444533(CHEMBL3099678)
Affinity DataIC50:  3.79E+5nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using PHOME as substrate incubated 15 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed