Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50042601
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428340BDBM50428340(CHEMBL2331712)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428342BDBM50428342(CHEMBL2331710)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428343BDBM50428343(CHEMBL2331708)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428343BDBM50428343(CHEMBL2331708)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428339BDBM50428339(CHEMBL2331714)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428339BDBM50428339(CHEMBL2331714)
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428340BDBM50428340(CHEMBL2331712)
Affinity DataIC50: 26nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428342BDBM50428342(CHEMBL2331710)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 52nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428344BDBM50428344(CHEMBL2331711)
Affinity DataIC50: 690nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed