Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50005383
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186055(US9163011, 9)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186075(US9163011, 30)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186049(US9163011, 3)
Affinity DataIC50: 7nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186080(US9163011, 35)
Affinity DataIC50: 7nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186048(US9163011, 2)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186055(US9163011, 9)
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186048(US9163011, 2)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186080(US9163011, 35)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186075(US9163011, 30)
Affinity DataIC50: 13nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186055(US9163011, 9)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186075(US9163011, 30)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186053(US9163011, 7)
Affinity DataIC50: 27nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186049(US9163011, 3)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186053(US9163011, 7)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186050(US9163011, 4)
Affinity DataIC50: 49nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186080(US9163011, 35)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186049(US9163011, 3)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186048(US9163011, 2)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186050(US9163011, 4)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186053(US9163011, 7)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1/2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186057(US9163011, 11)
Affinity DataIC50: 440nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186050(US9163011, 4)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186057(US9163011, 11)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186057(US9163011, 11)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human BACE2 extracellular domain expressed in baculovirus using Q-C(HS03)-lle-Asp-Leu-Ala-Val-Leu-Asp-HN-CH2-CH2-Mca as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed