Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50042991
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434284BDBM50434284(CHEMBL2386349)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434287BDBM50434287(CHEMBL2386346)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434283BDBM50434283(CHEMBL2386350)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434289BDBM50434289(CHEMBL2386344)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434290BDBM50434290(CHEMBL2386343)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434288BDBM50434288(CHEMBL2386345)
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434292BDBM50434292(CHEMBL2386169)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434285BDBM50434285(CHEMBL2386348)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434286BDBM50434286(CHEMBL2386347)
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434280BDBM50434280(CHEMBL2386168)
Affinity DataIC50: 52nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229787BDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434291BDBM50434291(CHEMBL2386170)
Affinity DataIC50: 209nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434281BDBM50434281(CHEMBL2386167)
Affinity DataIC50: 232nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434282BDBM50434282(CHEMBL2386351)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of N-terminal human recombinant MDM2 assessed as inhibition of protein interaction with p53 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed