Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50044626
TargetCathepsin D(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataKi:  3.08E+4nMAssay Description:Inhibition of cathepsin D in human liver using Lys-Lys-Pro-Ala-Glu-Phe-Phe-Ala-Leu-Lys as substrate by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of cathepsin D in human liver using Lys-Lys-Pro-Ala-Glu-Phe-Phe-Ala-Leu-Lys as substrate by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataKi:  4.16E+5nMAssay Description:Inhibition of recombinant BACE-1 (unknown origin) expressed in Escherichia coli measured for 5 to 30 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataKi:  4.16E+5nMAssay Description:Inhibition of recombinant BACE-1 (unknown origin) expressed in Escherichia coli measured for 5 to 30 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataEC50:  2.17E+5nMAssay Description:Inhibition of BACE-1 in human SH-SY5Y cells expressing wild-type APP assessed as reduction in amyloid beta-40 production after 16 hrs by sandwich ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Cricetulus griseus)
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50023040(CHEMBL2272783)
Affinity DataEC50:  7.30E+4nMAssay Description:Inhibition of BACE-1 in CHO cells expressing wild-type APP assessed as reduction in amyloid beta-40 production after 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed