Compile Data Set for Download or QSAR
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Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50045155
TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047394(CHEMBL3309848)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047406(CHEMBL3310738)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047371(CHEMBL3310749)
Affinity DataEC50:  4.37E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047372(CHEMBL3310751)
Affinity DataEC50:  3.80E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047373(CHEMBL3310760)
Affinity DataEC50:  3.63E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047374(CHEMBL3310743)
Affinity DataEC50:  2.88E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047375(CHEMBL3310766)
Affinity DataEC50:  2.82E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047377(CHEMBL3310767)
Affinity DataEC50:  2.57E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047378(CHEMBL3310745)
Affinity DataEC50:  2.51E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047379(CHEMBL3310747)
Affinity DataEC50:  2.34E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047380(CHEMBL3310756)
Affinity DataEC50:  2.34E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047381(CHEMBL3310748)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047382(CHEMBL3310752)
Affinity DataEC50:  1.82E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047383(CHEMBL3310755)
Affinity DataEC50:  1.78E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047384(CHEMBL3310750)
Affinity DataEC50:  1.66E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047385(CHEMBL3310753)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047386(CHEMBL3310746)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047387(CHEMBL3310757)
Affinity DataEC50:  871nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047388(CHEMBL3310744)
Affinity DataEC50:  794nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047389(CHEMBL3310761)
Affinity DataEC50:  692nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047390(CHEMBL3310742)
Affinity DataEC50:  661nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047391(CHEMBL3310759)
Affinity DataEC50:  631nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047392(CHEMBL3310764)
Affinity DataEC50:  631nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047393(CHEMBL3311002)
Affinity DataEC50:  631nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047395(CHEMBL3311000)
Affinity DataEC50:  617nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047396(CHEMBL3311001)
Affinity DataEC50:  437nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047397(CHEMBL3310763)
Affinity DataEC50:  316nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047398(CHEMBL3310765)
Affinity DataEC50:  288nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047399(CHEMBL3309849)
Affinity DataEC50:  282nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047400(CHEMBL3310762)
Affinity DataEC50:  275nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047401(CHEMBL3310758)
Affinity DataEC50:  269nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047402(CHEMBL3310741)
Affinity DataEC50:  229nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047403(CHEMBL3310998)
Affinity DataEC50:  229nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047394(CHEMBL3309848)
Affinity DataEC50:  129nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047404(CHEMBL3309850)
Affinity DataEC50:  123nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047405(CHEMBL3310999)
Affinity DataEC50:  95nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047406(CHEMBL3310738)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047407(CHEMBL3310739)
Affinity DataEC50:  48nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047408(CHEMBL3309852)
Affinity DataEC50:  44nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047409(CHEMBL3309851)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047409(CHEMBL3309851)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047408(CHEMBL3309852)
Affinity DataEC50:  43nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047407(CHEMBL3310739)
Affinity DataEC50:  48nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047406(CHEMBL3310738)
Affinity DataEC50:  86nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047405(CHEMBL3310999)
Affinity DataEC50:  95nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047404(CHEMBL3309850)
Affinity DataEC50:  124nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047394(CHEMBL3309848)
Affinity DataEC50:  129nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047402(CHEMBL3310741)
Affinity DataEC50:  228nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047403(CHEMBL3310998)
Affinity DataEC50:  228nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50047401(CHEMBL3310758)
Affinity DataEC50:  269nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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