Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50045225
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051038BDBM50051038(CHEMBL3318047)
Affinity DataIC50: 269nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051037BDBM50051037(CHEMBL3318048)
Affinity DataIC50: 407nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051038BDBM50051038(CHEMBL3318047)
Affinity DataIC50: 794nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 375 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051043BDBM50051043(CHEMBL3318052)
Affinity DataIC50: 794nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 375 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051037BDBM50051037(CHEMBL3318048)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 375 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051042BDBM50051042(CHEMBL3318053)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 375 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051041BDBM50051041(CHEMBL3318044)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051040BDBM50051040(CHEMBL3318045)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051045BDBM50051045(CHEMBL3318050)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051040BDBM50051040(CHEMBL3318045)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051046BDBM50051046(CHEMBL3318049)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051041BDBM50051041(CHEMBL3318044)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051039BDBM50051039(CHEMBL3318046)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051044BDBM50051044(CHEMBL3318051)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake treated with compound irradiated at 350 nm for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051039BDBM50051039(CHEMBL3318046)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of mouse GAT1 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051038BDBM50051038(CHEMBL3318047)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of mouse GAT3 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051038BDBM50051038(CHEMBL3318047)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of mouse GAT2 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051038BDBM50051038(CHEMBL3318047)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of mouse GAT4 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051037BDBM50051037(CHEMBL3318048)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse GAT3 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051037BDBM50051037(CHEMBL3318048)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of mouse GAT4 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051037BDBM50051037(CHEMBL3318048)
Affinity DataIC50: 6.46E+4nMAssay Description:Inhibition of mouse GAT2 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051039BDBM50051039(CHEMBL3318046)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of mouse GAT3 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051040BDBM50051040(CHEMBL3318045)
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of mouse GAT3 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051040BDBM50051040(CHEMBL3318045)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of mouse GAT4 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051039BDBM50051039(CHEMBL3318046)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of mouse GAT2 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051040BDBM50051040(CHEMBL3318045)
Affinity DataIC50: 3.39E+5nMAssay Description:Inhibition of mouse GAT2 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051039BDBM50051039(CHEMBL3318046)
Affinity DataIC50: 5.62E+5nMAssay Description:Inhibition of mouse GAT4 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051041BDBM50051041(CHEMBL3318044)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT4 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051041BDBM50051041(CHEMBL3318044)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT2 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051041BDBM50051041(CHEMBL3318044)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT3 stably expressed in HEK293 assessed as inhibition of [3H]GABA uptake after 25 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed