Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006223
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497944BDBM50497944(CHEMBL3323418)
Affinity DataIC50: 900nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497947BDBM50497947(CHEMBL3323415)
Affinity DataIC50: 2.10E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497960BDBM50497960(CHEMBL3323413)
Affinity DataIC50: 2.20E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482138BDBM50482138(CHEMBL495336)
Affinity DataIC50: 2.30E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497962BDBM50497962(CHEMBL3323408)
Affinity DataIC50: 2.90E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497946BDBM50497946(CHEMBL3323414)
Affinity DataIC50: 3.60E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497952BDBM50497952(CHEMBL3323405)
Affinity DataIC50: 4.10E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497953BDBM50497953(CHEMBL3323406)
Affinity DataIC50: 4.50E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497951BDBM50497951(CHEMBL3323403)
Affinity DataIC50: 4.80E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497961BDBM50497961(CHEMBL3323416)
Affinity DataIC50: 5.20E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497948BDBM50497948(CHEMBL3323417)
Affinity DataIC50: 5.20E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497950BDBM50497950(CHEMBL3323400)
Affinity DataIC50: 5.80E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289704BDBM50289704(CHEMBL260775)
Affinity DataIC50: 6.00E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497943BDBM50497943(CHEMBL3323410)
Affinity DataIC50: 6.60E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497942BDBM50497942(CHEMBL3323401)
Affinity DataIC50: 6.60E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497954BDBM50497954(CHEMBL3323411)
Affinity DataIC50: 6.90E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497958BDBM50497958(CHEMBL3323412)
Affinity DataIC50: 7.20E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497959BDBM50497959(CHEMBL3323409)
Affinity DataIC50: 8.30E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497957BDBM50497957(CHEMBL3323407)
Affinity DataIC50: 8.70E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497956BDBM50497956(CHEMBL3323402)
Affinity DataIC50: 8.80E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497949BDBM50497949(CHEMBL3323399)
Affinity DataIC50: 8.90E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497945BDBM50497945(CHEMBL3323404)
Affinity DataIC50: 9.20E+3nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50497955BDBM50497955(CHEMBL3323398)
Affinity DataIC50: 1.10E+4nMAssay Description:Correction of defective trafficking of human deltaF508 mutant CFTR protein expressed in FRT epithelial cells coexpressing YFP-H148Q/I152L protein ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed