Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50006262
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498270(CHEBI:52082 | HOE-33258 | HOECHST 33258)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498271(CHEMBL3581009)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498270(CHEBI:52082 | HOE-33258 | HOECHST 33258)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of human DNA topoisomerase-2 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50394837(HOE-33342 | CHEMBL343002)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498269(CHEMBL3581012)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498272(CHEMBL3581010)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498273(CHEMBL3581011)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498271(CHEMBL3581009)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of human DNA topoisomerase-2 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed