Compile Data Set for Download or QSAR
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Found 11 Enz. Inhib. hit(s) with all data for entry = 50045345
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058062(CHEMBL3323128)
Affinity DataIC50:  38nMAssay Description:Inhibition of human PDE4B expressed in Sf21 cells using cAMP substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058062(CHEMBL3323128)
Affinity DataIC50:  950nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058066(CHEMBL3323131)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058067(CHEMBL3323130)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058065(CHEMBL3323132)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058061(CHEMBL3323127)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058064(CHEMBL3323133)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058068(CHEMBL3321771)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058063(CHEMBL3323129)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50058060(CHEMBL3323123)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Trypanosoma brucei recombinant PDEB1 pre-incubated for 5 mins prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed