Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022608
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataKi:  0.330nMAssay Description:Inhibition of full length human SETD7 (1 to 366 residues) expressed in Escherichia coli BL21 (DE3) V2R-pRARE assessed as apparent inhibition constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataIC50: 2nMAssay Description:Inhibition of wildtype full length human SETD7 (1 to 366 residues) expressed in Escherichia coli BL21 (DE3) V2R-pRARE using biotinylated H3 (1-25) pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to biotinylated SETD7 (unknown origin) assessed as dissociation constant in presence of SAM in flow and wash buffer by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50653009(CHEMBL5712041)
Affinity DataIC50: 110nMAssay Description:Inhibition of wildtype full length human SETD7 (1 to 366 residues) expressed in Escherichia coli BL21 (DE3) V2R-pRARE using biotinylated H3 (1-25) pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50653008(CHEMBL5712060)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wildtype full length human SETD7 (1 to 366 residues) expressed in Escherichia coli BL21 (DE3) V2R-pRARE using biotinylated H3 (1-25) pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human alpha 2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMotilin receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human motilin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBombesin receptor subtype-3(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50075073(CHEMBL3414622)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human BB3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed