Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50046225
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101088BDBM50101088(CHEMBL3326220)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100983BDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101091BDBM50101091(CHEMBL3326223)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101088BDBM50101088(CHEMBL3326220)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100991BDBM50100991(CHEMBL3325879)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100983BDBM50100983(CHEMBL3326224)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100993BDBM50100993(CHEMBL3325881)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101090BDBM50101090(CHEMBL3326222)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100993BDBM50100993(CHEMBL3325881)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100986BDBM50100986(CHEMBL3325747)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100982BDBM50100982(CHEMBL3326225)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells at 1 uM after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100992BDBM50100992(CHEMBL3325880)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100983BDBM50100983(CHEMBL3326224)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100989BDBM50100989(CHEMBL3325751)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100986BDBM50100986(CHEMBL3325747)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100983BDBM50100983(CHEMBL3326224)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to human delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100992BDBM50100992(CHEMBL3325880)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101089BDBM50101089(CHEMBL3326221)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101089BDBM50101089(CHEMBL3326221)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100990BDBM50100990(CHEMBL3325878)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101091BDBM50101091(CHEMBL3326223)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101090BDBM50101090(CHEMBL3326222)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100989BDBM50100989(CHEMBL3325751)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100990BDBM50100990(CHEMBL3325878)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100987BDBM50100987(CHEMBL3325748)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100982BDBM50100982(CHEMBL3326225)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100991BDBM50100991(CHEMBL3325879)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100984BDBM50100984(CHEMBL3325745)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100987BDBM50100987(CHEMBL3325748)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100995BDBM50100995(CHEMBL3325883)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100994BDBM50100994(CHEMBL3325882)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100984BDBM50100984(CHEMBL3325745)
Affinity DataKi:  205nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100988BDBM50100988(CHEMBL3325749)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101092BDBM50101092(CHEMBL3326227)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101084BDBM50101084(CHEMBL3326219)
Affinity DataKi:  810nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100988BDBM50100988(CHEMBL3325749)
Affinity DataKi:  830nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101094BDBM50101094(CHEMBL3326226)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100985BDBM50100985(CHEMBL3325746)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101094BDBM50101094(CHEMBL3326226)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100993BDBM50100993(CHEMBL3325881)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101090BDBM50101090(CHEMBL3326222)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100993BDBM50100993(CHEMBL3325881)
Affinity DataEC50:  4.30E+4nMAssay Description:Agonist activity at human NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101090BDBM50101090(CHEMBL3326222)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed