Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50044651
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023607(CHEMBL3355579)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023606(CHEMBL3355580)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023605(CHEMBL3355581)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023605(CHEMBL3355581)
Affinity DataIC50: 181nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023606(CHEMBL3355580)
Affinity DataIC50: 742nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50023607(CHEMBL3355579)
Affinity DataIC50: 982nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide preincubated for 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed