Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50046286
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057402BDBM50057402(CHEMBL3322777)
Affinity DataIC50: 9nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103575BDBM50103575(CHEMBL3337585)
Affinity DataIC50: 9nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103573BDBM50103573(CHEMBL3337583)
Affinity DataIC50: 19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103586BDBM50103586(CHEMBL3337596)
Affinity DataIC50: 21nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103574BDBM50103574(CHEMBL3337584)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103591BDBM50103591(CHEMBL3337601)
Affinity DataIC50: 35nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103589BDBM50103589(CHEMBL3337599)
Affinity DataIC50: 41nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103576BDBM50103576(CHEMBL3337586)
Affinity DataIC50: 63nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103587BDBM50103587(CHEMBL3337597)
Affinity DataIC50: 64nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103592BDBM50103592(CHEMBL3337602)
Affinity DataIC50: 73nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103584BDBM50103584(CHEMBL3337595)
Affinity DataIC50: 73nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103577BDBM50103577(CHEMBL3337587)
Affinity DataIC50: 80nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103578BDBM50103578(CHEMBL3337589)
Affinity DataIC50: 103nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103585BDBM50103585(CHEMBL3337594)
Affinity DataIC50: 106nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103588BDBM50103588(CHEMBL3337598)
Affinity DataIC50: 109nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103584BDBM50103584(CHEMBL3337595)
Affinity DataIC50: 118nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103590BDBM50103590(CHEMBL3337600)
Affinity DataIC50: 124nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103573BDBM50103573(CHEMBL3337583)
Affinity DataIC50: 181nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103575BDBM50103575(CHEMBL3337585)
Affinity DataIC50: 217nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103583BDBM50103583(CHEMBL3337588)
Affinity DataIC50: 315nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057402BDBM50057402(CHEMBL3322777)
Affinity DataIC50: 331nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103574BDBM50103574(CHEMBL3337584)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103577BDBM50103577(CHEMBL3337587)
Affinity DataIC50: 358nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103589BDBM50103589(CHEMBL3337599)
Affinity DataIC50: 419nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103581BDBM50103581(CHEMBL3337592)
Affinity DataIC50: 439nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103578BDBM50103578(CHEMBL3337589)
Affinity DataIC50: 519nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057402BDBM50057402(CHEMBL3322777)
Affinity DataIC50: 572nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103580BDBM50103580(CHEMBL3337591)
Affinity DataIC50: 656nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103587BDBM50103587(CHEMBL3337597)
Affinity DataIC50: 690nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103587BDBM50103587(CHEMBL3337597)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103585BDBM50103585(CHEMBL3337594)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103586BDBM50103586(CHEMBL3337596)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103591BDBM50103591(CHEMBL3337601)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103590BDBM50103590(CHEMBL3337600)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103576BDBM50103576(CHEMBL3337586)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103581BDBM50103581(CHEMBL3337592)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103592BDBM50103592(CHEMBL3337602)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103588BDBM50103588(CHEMBL3337598)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103580BDBM50103580(CHEMBL3337591)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103583BDBM50103583(CHEMBL3337588)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103579BDBM50103579(CHEMBL3337590)
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057402BDBM50057402(CHEMBL3322777)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103582BDBM50103582(CHEMBL3337593)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103579BDBM50103579(CHEMBL3337590)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103582BDBM50103582(CHEMBL3337593)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed