Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50044834
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataKi:  2.87E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataKi:  5.53E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataKi:  9.97E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataKi:  1.03E+4nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031905(CHEMBL3360904)
Affinity DataKi:  1.49E+4nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031907(CHEMBL2337245)
Affinity DataKi:  1.79E+4nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031909(CHEMBL3360907)
Affinity DataKi:  1.92E+4nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031904(CHEMBL3360903)
Affinity DataKi:  2.62E+4nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031911(CHEMBL1299903)
Affinity DataKi:  4.10E+4nMAssay Description:Covalent irreversible inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031916(CHEMBL3360912)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1A(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 18(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031920(CHEMBL3360916)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 18(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1A(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031913(CHEMBL3360910)
Affinity DataIC50:  3.65E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  3.75E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  3.88E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031917(CHEMBL3360913)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031919(CHEMBL3360915)
Affinity DataIC50:  4.14E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031918(CHEMBL3360914)
Affinity DataIC50:  4.17E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031912(CHEMBL3360909)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1A(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50:  4.25E+4nMAssay Description:Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031946(CHEMBL3360917)
Affinity DataIC50:  4.87E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  5.07E+4nMAssay Description:Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  6.06E+4nMAssay Description:Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50:  6.38E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1A(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  6.78E+4nMAssay Description:Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 1G(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  7.48E+4nMAssay Description:Inhibition of PPM1G (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50:  7.85E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031914(CHEMBL3196685)
Affinity DataIC50:  7.95E+4nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031915(CHEMBL3360911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 18(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase Slingshot homolog 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase Slingshot homolog 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase Slingshot homolog 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase Slingshot homolog 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 18(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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