Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50044864
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033406BDBM50033406(CHEMBL3357658)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448549BDBM50448549(CHEMBL3127106)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033408BDBM50033408(CHEMBL3357656)
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033406BDBM50033406(CHEMBL3357658)
Affinity DataIC50: 13nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033405BDBM50033405(CHEMBL3357659)
Affinity DataIC50: 26nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033400BDBM50033400(CHEMBL3357664)
Affinity DataIC50: 27nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033405BDBM50033405(CHEMBL3357659)
Affinity DataIC50: 37nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033399BDBM50033399(CHEMBL3357665)
Affinity DataIC50: 37nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033411BDBM50033411(CHEMBL3357670)
Affinity DataIC50: 41nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033409BDBM50033409(CHEMBL3357668)
Affinity DataIC50: 41nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033398BDBM50033398(CHEMBL3357666)
Affinity DataIC50: 48nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033408BDBM50033408(CHEMBL3357656)
Affinity DataIC50: 48nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033398BDBM50033398(CHEMBL3357666)
Affinity DataIC50: 51nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033399BDBM50033399(CHEMBL3357665)
Affinity DataIC50: 52nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033397BDBM50033397(CHEMBL3357667)
Affinity DataIC50: 55nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033412BDBM50033412(CHEMBL3357671)
Affinity DataIC50: 56nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033413BDBM50033413(CHEMBL3357672)
Affinity DataIC50: 56nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033403BDBM50033403(CHEMBL3357661)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033403BDBM50033403(CHEMBL3357661)
Affinity DataIC50: 76nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033413BDBM50033413(CHEMBL3357672)
Affinity DataIC50: 81nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033400BDBM50033400(CHEMBL3357664)
Affinity DataIC50: 86nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033412BDBM50033412(CHEMBL3357671)
Affinity DataIC50: 89nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033397BDBM50033397(CHEMBL3357667)
Affinity DataIC50: 93nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033410BDBM50033410(CHEMBL3357669)
Affinity DataIC50: 98nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033410BDBM50033410(CHEMBL3357669)
Affinity DataIC50: 98nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033410BDBM50033410(CHEMBL3357669)
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033410BDBM50033410(CHEMBL3357669)
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033409BDBM50033409(CHEMBL3357668)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033402BDBM50033402(CHEMBL3357662)
Affinity DataIC50: 130nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033411BDBM50033411(CHEMBL3357670)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033402BDBM50033402(CHEMBL3357662)
Affinity DataIC50: 210nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033401BDBM50033401(CHEMBL3357663)
Affinity DataIC50: 550nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033407BDBM50033407(CHEMBL3357657)
Affinity DataIC50: 700nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033404BDBM50033404(CHEMBL3357660)
Affinity DataIC50: 759nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033401BDBM50033401(CHEMBL3357663)
Affinity DataIC50: 810nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033404BDBM50033404(CHEMBL3357660)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033405BDBM50033405(CHEMBL3357659)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033407BDBM50033407(CHEMBL3357657)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033408BDBM50033408(CHEMBL3357656)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033406BDBM50033406(CHEMBL3357658)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033402BDBM50033402(CHEMBL3357662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033407BDBM50033407(CHEMBL3357657)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033400BDBM50033400(CHEMBL3357664)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033411BDBM50033411(CHEMBL3357670)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033397BDBM50033397(CHEMBL3357667)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033403BDBM50033403(CHEMBL3357661)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033409BDBM50033409(CHEMBL3357668)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033398BDBM50033398(CHEMBL3357666)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033413BDBM50033413(CHEMBL3357672)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033410BDBM50033410(CHEMBL3357669)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
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