Compile Data Set for Download or QSAR
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Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50044906
TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035709(CHEMBL3359895)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035712(CHEMBL3359894)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035710(CHEMBL3359893)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035721(CHEMBL3359885)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035709(CHEMBL3359895)
Affinity DataIC50:  98nMAssay Description:Inhibition of ChK1 in human HT-29 cells assessed as phospho-histone H3 by Isobologram assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035714(CHEMBL3359891)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035788(CHEMBL3359884)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035720(CHEMBL3359886)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035716(CHEMBL3359889)
Affinity DataIC50:  470nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035711(CHEMBL3359896)
Affinity DataIC50:  675nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035715(CHEMBL3359890)
Affinity DataIC50:  690nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035713(CHEMBL3359892)
Affinity DataIC50:  820nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035804(CHEMBL3359881)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035718(CHEMBL3359887)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035803(CHEMBL3359882)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035792(CHEMBL3359883)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035710(CHEMBL3359893)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ChK1 in human HT-29 cells assessed as phospho-histone H3 by Isobologram assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035717(CHEMBL3359888)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed