Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50022494
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human RIP3 kinase activity by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519649(CHEMBL4439913)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human RIP3 kinase domain (1 to 328 residues) expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50621577(CHEMBL4779280)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human RIP3 kinase activity by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50621577(CHEMBL4779280)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human RIP3 kinase domain (1 to 328 residues) expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human RIP3 kinase activity by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human RIP3 kinase domain (1 to 328 residues) expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed