Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50046174 Sort by
TargetKappa-type opioid receptor(Rat)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataKd:  1nMAssay Description:Binding affinity to rat kappa opioid receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097703(CHEMBL3590199)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097704(CHEMBL3590200)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097700(CHEMBL3590196)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097701(CHEMBL3590197)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097699(CHEMBL3590195)
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097696(CHEMBL3590192)
Affinity DataIC50: 10nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097697(CHEMBL3590193)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50: 29nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097698(CHEMBL3590194)
Affinity DataIC50: 33nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097699(CHEMBL3590195)
Affinity DataIC50: 49nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097701(CHEMBL3590197)
Affinity DataIC50: 76nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097703(CHEMBL3590199)
Affinity DataIC50: 84nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097702(CHEMBL3590198)
Affinity DataIC50: 85nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097704(CHEMBL3590200)
Affinity DataIC50: 87nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097704(CHEMBL3590200)
Affinity DataIC50: 93nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097699(CHEMBL3590195)
Affinity DataIC50: 104nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097701(CHEMBL3590197)
Affinity DataIC50: 104nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097705(CHEMBL3590201)
Affinity DataIC50: 106nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097703(CHEMBL3590199)
Affinity DataIC50: 107nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 113nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM54817(N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(4-methy...)
Affinity DataIC50: 138nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097700(CHEMBL3590196)
Affinity DataIC50: 143nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71581(cid_44620907 | N-[2-[(4-bromophenyl)methyl-propan-...)
Affinity DataIC50: 168nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097700(CHEMBL3590196)
Affinity DataIC50: 186nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097697(CHEMBL3590193)
Affinity DataIC50: 258nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097698(CHEMBL3590194)
Affinity DataIC50: 314nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097698(CHEMBL3590194)
Affinity DataIC50: 350nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097697(CHEMBL3590193)
Affinity DataIC50: 388nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097696(CHEMBL3590192)
Affinity DataIC50: 392nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097696(CHEMBL3590192)
Affinity DataIC50: 400nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM54817(N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(4-methy...)
Affinity DataIC50: 403nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50: 406nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50: 478nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM54817(N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(4-methy...)
Affinity DataIC50: 591nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71581(cid_44620907 | N-[2-[(4-bromophenyl)methyl-propan-...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity against human kappa opioid receptor by DiscoveRx beta-arrestin2 recruitment based PathHunter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097705(CHEMBL3590201)
Affinity DataIC50: 710nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71581(cid_44620907 | N-[2-[(4-bromophenyl)methyl-propan-...)
Affinity DataIC50: 750nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM54817(N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(4-methy...)
Affinity DataIC50: 860nMAssay Description:Antagonist activity against human kappa opioid receptor by DiscoveRx beta-arrestin2 recruitment based PathHunter assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097702(CHEMBL3590198)
Affinity DataIC50: 880nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 930nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71581(cid_44620907 | N-[2-[(4-bromophenyl)methyl-propan-...)
Affinity DataIC50: 937nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097694(CHEMBL3590190)
Affinity DataIC50: 1.12E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097702(CHEMBL3590198)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097705(CHEMBL3590201)
Affinity DataIC50: 1.34E+3nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM71580(cid_44620897 | N-[2-(1,3-dihydroisoindol-2-yl)ethy...)
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM75578(cid_45479170 | N-(1-benzylpyrrolidin-3-yl)-4-[[(4-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Jump to: