Compile Data Set for Download or QSAR
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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50045714
LigandPNGBDBM50078161(CHEMBL3417702)
Affinity DataKi:  0.200nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078159(CHEMBL3417700)
Affinity DataKi:  0.240nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078162(CHEMBL3417703)
Affinity DataKi:  0.310nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi:  0.430nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078163(CHEMBL3417704)
Affinity DataKi:  0.450nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078164(CHEMBL3417705)
Affinity DataKi:  0.480nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  1.5nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078165(CHEMBL3417706)
Affinity DataKi:  1.80nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50078158(CHEMBL3417699)
Affinity DataKi:  2nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078157(CHEMBL3417698)
Affinity DataKi:  2.30nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078159(CHEMBL3417700)
Affinity DataKi:  2.70nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  4nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078161(CHEMBL3417702)
Affinity DataKi:  4.90nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi:  6nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078163(CHEMBL3417704)
Affinity DataKi:  7.90nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078162(CHEMBL3417703)
Affinity DataKi:  8.80nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  9nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi: <10nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078158(CHEMBL3417699)
Affinity DataKi:  12nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078164(CHEMBL3417705)
Affinity DataKi:  12nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  21nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi: <30nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  35nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi:  35nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078165(CHEMBL3417706)
Affinity DataKi:  98nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50078157(CHEMBL3417698)
Affinity DataKi:  114nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078150(CHEMBL3417581)
Affinity DataKi:  130nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078153(CHEMBL3417693)
Affinity DataKi:  150nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078152(CHEMBL3417692)
Affinity DataKi:  160nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50424734(CHEMBL2314198)
Affinity DataKi:  340nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  360nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50424734(CHEMBL2314198)
Affinity DataKi:  400nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  470nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBcl-2-like protein 2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Inhibition of BCL-W (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from BCL-XL (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from BCL2 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBcl-2-related protein A1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Inhibition of BCL2-A1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078155(CHEMBL3417697)
Affinity DataKi:  1.45E+3nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078166(CHEMBL3417580)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant MCL1 (unknown origin) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078150(CHEMBL3417581)
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50424734(CHEMBL2314198)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50078152(CHEMBL3417692)
Affinity DataKi:  8.20E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi:  8.60E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50078153(CHEMBL3417693)
Affinity DataKi:  9.10E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078166(CHEMBL3417580)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of BCL-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078166(CHEMBL3417580)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of BCL-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078156(CHEMBL3417696)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed